KCNE2 anticorps (Internal Region)

N° du produit ABIN6258938

Détail du produit anti-KCNE2 anticorps

Antigène: KCNE2 (Potassium Voltage-Gated Channel, Isk-Related Family, Member 2 (KCNE2))

Épitope: Internal Region

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KCNE2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: KCNE2 Antibody detects endogenous levels of total KCNE2.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human KCNE2, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Date de péremption: 12 months

Détails sur KCNE2

Antigène: KCNE2 (Potassium Voltage-Gated Channel, Isk-Related Family, Member 2 (KCNE2))

Autre désignation: KCNE2 (KCNE2 Produits)

Synonymes: anticorps ATFB4, anticorps LQT5, anticorps LQT6, anticorps MIRP1, anticorps Mirp1, anticorps MiRP1, anticorps 2200002I16Rik, anticorps AW048273, anticorps potassium voltage-gated channel subfamily E regulatory subunit 2, anticorps potassium voltage-gated channel, Isk-related subfamily, gene 2, anticorps KCNE2, anticorps Kcne2

Sujet:

Description: Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. Associated with KCNH2/HERG is proposed to form the rapidly activating component of the delayed rectifying potassium current in heart (IKr). May associate with KCNQ2 and/or KCNQ3 and modulate the native M-type current. May associate with HCN1 and HCN2 and increase potassium current. Interacts with KCNQ1, forms a heterooligomer complex leading to currents with an apparently instantaneous activation, a rapid deactivation process and a linear current-voltage relationship and decreases the amplitude of the outward current (PubMed:11101505).

Gene: KCNE2

Poids moléculaire: ?14 kDa

ID gène: 9992

UniProt: Q9Y6J6