IFITM1 anticorps (N-Term)

N° du produit ABIN6259087

Détail du produit anti-IFITM1 anticorps

Antigène: IFITM1 (Interferon-Induced Transmembrane Protein 1 (IFITM1))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IFITM1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: IFITM1 Antibody detects endogenous levels of total IFITM1.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human IFITM1, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Date de péremption: 12 months

Détails sur IFITM1

Antigène: IFITM1 (Interferon-Induced Transmembrane Protein 1 (IFITM1))

Autre désignation: IFITM1 (IFITM1 Produits)

Synonymes: anticorps 9-27, anticorps CD225, anticorps DSPA2a, anticorps IFI17, anticorps LEU13, anticorps 1110036C17Rik, anticorps Mil-2, anticorps Mil2, anticorps interferon induced transmembrane protein 1, anticorps interferon induced transmembrane protein 1 (9-27), anticorps Ifitm1, anticorps IFITM1

Sujet:

Description: IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry and SARS-CoV S protein-mediated viral entry. Also implicated in cell adhesion and control of cell growth and migration. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activation or by arresting cell growth in G1 phase in a p53-dependent manner. Acts as a positive regulator of osteoblast differentiation.

Gene: IFITM1

Poids moléculaire: 14 kDa

ID gène: 8519

UniProt: P13164