ANG anticorps (Internal Region)

N° du produit ABIN6259924

Détail du produit anti-ANG anticorps

Antigène: ANG (Angiogenin (ANG))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ANG est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificité: Angiogenin Antibody detects endogenous levels of total Angiogenin.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human Angiogenin, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur ANG

Antigène: ANG (Angiogenin (ANG))

Autre désignation: ANG (ANG Produits)

Synonymes: anticorps ALS9, anticorps HEL168, anticorps RNASE4, anticorps RNASE5, anticorps ANG, anticorps AI385586, anticorps Ang1, anticorps Rnase5, anticorps Rnase5a, anticorps ANG1, anticorps angiogenin, anticorps angiogenin, ribonuclease, RNase A family, 5, anticorps ribonuclease A family member k6, anticorps ANG, anticorps Ang, anticorps RNASE6

Sujet:

Description: Binds to actin on the surface of endothelial cells, once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA. Cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs). Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo.

Gene: ANG

Poids moléculaire: 17kDa

ID gène: 283

UniProt: P03950