Antizyme Inhibitor 1 anticorps (Internal Region)

N° du produit ABIN6259946

Détail du produit anti-Antizyme Inhibitor 1 anticorps

Antigène: Antizyme Inhibitor 1 (AZIN1)

Épitope: Internal Region

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Antizyme Inhibitor 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificité: Antizyme inhibitor 1 Antibody detects endogenous levels of total Antizyme inhibitor 1.

Homologie: Pig,Bovine,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human Antizyme inhibitor 1, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur Antizyme Inhibitor 1

Antigène: Antizyme Inhibitor 1 (AZIN1)

Autre désignation: AZIN1 (AZIN1 Produits)

Synonymes: anticorps OAZI, anticorps OAZIN, anticorps ODC1L, anticorps 1700085L02Rik, anticorps AI414949, anticorps Oazi, anticorps Oazin, anticorps AZIN1, anticorps azin1, anticorps oazin, anticorps wu:fj32d12, anticorps MGC81852, anticorps wu:fc93f10, anticorps zgc:110131, anticorps antizyme inhibitor 1, anticorps antizyme inhibitor 1b, anticorps antizyme inhibitor 1 L homeolog, anticorps antizyme inhibitor 1a, anticorps AZIN1, anticorps Azin1, anticorps azin1b, anticorps azin1.L, anticorps azin1, anticorps azin1a

Sujet:

Description: Antizyme inhibitor (AZI) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake. AZI is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizymes (AZs) OAZ1, OAZ2 and OAZ3 on ODC activity by competing with ODC for antizyme-binding (PubMed:17900240, PubMed:26305948). Inhibits antizyme-dependent ODC degradation and releases ODC monomers from their inactive complex with antizymes, leading to formation of the catalytically active ODC homodimer and restoring polyamine production (PubMed:17900240).

Gene: AZIN1

Poids moléculaire: 49.5 kDa

ID gène: 51582

UniProt: O14977