ATP6V0A2 anticorps (Internal Region)

N° du produit ABIN6260132

Détail du produit anti-ATP6V0A2 anticorps

Antigène: ATP6V0A2 (ATPase, H+ Transporting, Lysosomal V0 Subunit A2 (ATP6V0A2))

Épitope: Internal Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATP6V0A2 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: ATP6V0A2 Antibody detects endogenous levels of total ATP6V0A2.

Homologie: Bovine,Horse,Sheep,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human ATP6V0A2, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur ATP6V0A2

Antigène: ATP6V0A2 (ATPase, H+ Transporting, Lysosomal V0 Subunit A2 (ATP6V0A2))

Autre désignation: ATP6V0A2 (ATP6V0A2 Produits)

Synonymes: anticorps A2, anticorps ARCL, anticorps ARCL2A, anticorps ATP6A2, anticorps ATP6N1D, anticorps J6B7, anticorps RTF, anticorps STV1, anticorps TJ6, anticorps TJ6M, anticorps TJ6S, anticorps VPH1, anticorps WSS, anticorps 8430408C20Rik, anticorps AI385560, anticorps ATP6a2, anticorps AW489264, anticorps Atp6n1d, anticorps Atp6n2, anticorps C76904, anticorps ISF, anticorps SHIF, anticorps Stv1, anticorps TJ6s, anticorps Tj6, anticorps V-ATPase 116 kDa, anticorps V-ATPase a2, anticorps Cc1-3, anticorps J6b7, anticorps atp6v0a2, anticorps si:ch211-199i18.4, anticorps si:ch211-106a19.2, anticorps ATPase H+ transporting V0 subunit a2, anticorps ATPase, H+ transporting, lysosomal V0 subunit A2, anticorps ATPase, H+ transporting, lysosomal V0 subunit a2a, anticorps ATPase, H+ transporting, lysosomal V0 subunit a2b, anticorps ATP6V0A2, anticorps Atp6v0a2, anticorps atp6v0a2a, anticorps atp6v0a2b

Sujet:

Description: Part of the proton channel of V-ATPases. Essential component of the endosomal  pH -sensing machinery. May play a role in maintaining the Golgi functions, such as glycosylation maturation, by controlling the Golgi  pH . In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe2+ prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (PubMed:28296633).

Gene: ATP6V0A2

Poids moléculaire: 98 kDa

ID gène: 23545

UniProt: Q9Y487

Pathways: Transition Metal Ion Homeostasis, Proton Transport