ATP8A1 anticorps (Internal Region)

N° du produit ABIN6260139

Détail du produit anti-ATP8A1 anticorps

Antigène: ATP8A1 (ATPase, Class I, Type 8A, Member 1 (ATP8A1))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATP8A1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificité: ATP8A1 Antibody detects endogenous levels of total ATP8A1.

Homologie: Pig,Bovine,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human ATP8A1, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur ATP8A1

Antigène: ATP8A1 (ATPase, Class I, Type 8A, Member 1 (ATP8A1))

Autre désignation: ATP8A1 (ATP8A1 Produits)

Synonymes: anticorps ATPASEII, anticorps ATPIA, anticorps ATPP2, anticorps AI481521, anticorps AI853962, anticorps APLT, anticorps AW743152, anticorps AW822227, anticorps Atp3a2, anticorps B230107D19Rik, anticorps ClassI, anticorps mKIAA4233, anticorps ATPase phospholipid transporting 8A1, anticorps ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1, anticorps Atp8a1, anticorps ATP8A1

Sujet:

Description: Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. In vitro, its ATPase activity is selectively and stereospecifically stimulated by phosphatidylserine (PS). The flippase complex ATP8A1:TMEM30A seems to play a role in regulation of cell migration probably involving flippase-mediated translocation of phosphatidylethanolamine (PE) at the plasma membrane. Acts as aminophospholipid translocase at the plasma membrane in neuronal cells.

Gene: ATP8A1

Poids moléculaire: 120 kDa

ID gène: 10396

UniProt: Q9Y2Q0