CYFIP1 anticorps (Internal Region)

N° du produit ABIN6261160

Détail du produit anti-CYFIP1 anticorps

Antigène: CYFIP1 (Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1))

Épitope: Internal Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYFIP1 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: CYFIP1 Antibody detects endogenous levels of total CYFIP1.

Homologie: Zebrafish,Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human CYFIP1, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur CYFIP1

Antigène: CYFIP1 (Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1))

Autre désignation: CYFIP1 (CYFIP1 Produits)

Synonymes: anticorps TUBGCP5, anticorps P140SRA-1, anticorps SHYC, anticorps SRA1, anticorps E030028J09Rik, anticorps P140sra1, anticorps Shyc, anticorps Sra-1, anticorps Sra1, anticorps l(7)1Rl, anticorps l71Rl, anticorps l7Rl1, anticorps mKIAA0068, anticorps pl-1, anticorps CY, anticorps CYFIP, anticorps fb15a06, anticorps wu:fb15a06, anticorps cytoplasmic FMR1 interacting protein 1, anticorps CYFIP1, anticorps cyfip1, anticorps Cyfip1

Sujet:

Description: Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. Promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA (By similarity). Regulates formation of membrane ruffles and lamellipodia. Plays a role in axon outgrowth. Binds to F-actin but not to RNA. Part of the WAVE complex that regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. Regulator of epithelial morphogenesis. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity). May act as an invasion suppressor in cancers.

Gene: CYFIP1

Poids moléculaire: 145 kDa

ID gène: 23191

UniProt: Q7L576