CYP4F2 anticorps (N-Term)

N° du produit ABIN6261173

Détail du produit anti-CYP4F2 anticorps

Antigène: CYP4F2 (Cytochrome P450, Family 4, Subfamily F, Polypeptide 2 (CYP4F2))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYP4F2 est non-conjugé

Application: ELISA, Western Blotting (WB)

Specificité: CYP4F2 Antibody detects endogenous levels of total CYP4F2.

Homologie: Pig,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human CYP4F2, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur CYP4F2

Antigène: CYP4F2 (Cytochrome P450, Family 4, Subfamily F, Polypeptide 2 (CYP4F2))

Autre désignation: CYP4F2 (CYP4F2 Produits)

Synonymes: anticorps CPF2, anticorps MGC126966, anticorps cytochrome P450 family 4 subfamily F member 2, anticorps cytochrome P450, family 4, subfamily F, polypeptide 2, anticorps cytochrome P450 family 4 subfamily F member 2 L homeolog, anticorps CYP4F2, anticorps cyp4f2.L

Sujet:

Description: Omega-hydroxylase that oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids and xenobiotics. Plays a key role in vitamin K catabolism by mediating omega-hydroxylation of vitamin K1 (phylloquinone), and menaquinone-4 (MK-4), a form of vitamin K2. Hydroxylation of phylloquinone and MK-4 probably regulates blood coagulation (PubMed:19297519, PubMed:24138531). Also shows arachidonic acid omega-hydroxylase activity in kidney, by mediating conversion of arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE), possibly influencing blood pressure control (PubMed:10660572, PubMed:17341693, PubMed:18574070). Also acts as a leukotriene-B4 omega-hydroxylase by mediating conversion of leukotriene-B4 (LTB4) to its omega-hydroxylated metabolite 20-hydroxyleukotriene-B4 (20-OH LTB4) (PubMed:8026587, PubMed:9799565).

Gene: CYP4F2

Poids moléculaire: 60kDa

ID gène: 8529

UniProt: P78329

Pathways: Monocarboxylic Acid Catabolic Process