DMAP1 anticorps (Internal Region)

N° du produit ABIN6261316

Détail du produit anti-DMAP1 anticorps

Antigène: DMAP1 (DNA Methyltransferase 1-Associated Protein 1 (DMAP1))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DMAP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificité: DMAP1 Antibody detects endogenous levels of total DMAP1.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human DMAP1, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur DMAP1

Antigène: DMAP1 (DNA Methyltransferase 1-Associated Protein 1 (DMAP1))

Autre désignation: DMAP1 (DMAP1 Produits)

Synonymes: anticorps Afu4g07380, anticorps T8I13.5, anticorps DNMAP1, anticorps DNMTAP1, anticorps EAF2, anticorps MEAF2, anticorps SWC4, anticorps zgc:55593, anticorps dnmap1, anticorps dnmtap1, anticorps eaf2, anticorps meaf2, anticorps swc4, anticorps 1500016M21Rik, anticorps Dmtap1, anticorps mKIAA1425, anticorps DNA methyltransferase 1-associated protein DMAP1, anticorps DNA methyltransferase 1-associated protein 1, anticorps DNA methyltransferase 1 associated protein 1, anticorps myb-like transcription factor family protein, anticorps DNA methyltransferase 1 associated protein 1 L homeolog, anticorps AFUA_4G07380, anticorps NFIA_108840, anticorps ACLA_046700, anticorps CpipJ_CPIJ017959, anticorps Bm1_47540, anticorps PMAA_026820, anticorps AFLA_112450, anticorps TSTA_072020, anticorps BDBG_02603, anticorps AT2G47210, anticorps CpipJ_CPIJ007438, anticorps DMAP1, anticorps dmap1, anticorps dmap1.L, anticorps Dmap1

Sujet:

Description: Involved in transcription repression and activation. Its interaction with HDAC2 may provide a mechanism for histone deacetylation in heterochromatin following replication of DNA at late firing origins. Can also repress transcription independently of histone deacetylase activity. May specifically potentiate DAXX-mediated repression of glucocorticoid receptor-dependent transcription. Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Participates in the nuclear localization of URI1 and increases its transcriptional corepressor activity.

Gene: DMAP1

Poids moléculaire: 53 kDa

ID gène: 55929

UniProt: Q9NPF5