ESRP1 anticorps (Internal Region)

N° du produit ABIN6261608

Détail du produit anti-ESRP1 anticorps

Antigène: ESRP1 (Epithelial Splicing Regulatory Protein 1 (ESRP1))

Épitope: Internal Region

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ESRP1 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: ESRP1 Antibody detects endogenous levels of total ESRP1.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human ESRP1, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur ESRP1

Antigène: ESRP1 (Epithelial Splicing Regulatory Protein 1 (ESRP1))

Autre désignation: ESRP1 (ESRP1 Produits)

Synonymes: anticorps rbm35a, anticorps RBM35A, anticorps RMB35A, anticorps 2210008M09Rik, anticorps A630065D16, anticorps BC031468, anticorps Rbm35a, anticorps RGD1560481, anticorps wu:fi28a07, anticorps zgc:154050, anticorps epithelial splicing regulatory protein 1, anticorps epithelial splicing regulatory protein 1 L homeolog, anticorps ESRP1, anticorps esrp1.L, anticorps Esrp1, anticorps esrp1

Sujet:

Description: mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.

Gene: ESRP1

Poids moléculaire: 76 kDa

ID gène: 54845

UniProt: Q6NXG1