GTF2H4 anticorps (Internal Region)

N° du produit ABIN6262124

Détail du produit anti-GTF2H4 anticorps

Antigène: GTF2H4 (General Transcription Factor IIH, Polypeptide 4, 52kDa (GTF2H4))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GTF2H4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: GTF2H4 Antibody detects endogenous levels of total GTF2H4.

Homologie: Bovine,Sheep,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human GTF2H4, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur GTF2H4

Antigène: GTF2H4 (General Transcription Factor IIH, Polypeptide 4, 52kDa (GTF2H4))

Autre désignation: GTF2H4 (GTF2H4 Produits)

Synonymes: anticorps gtf2h4.2, anticorps tfb2, anticorps tfiih, anticorps DDBDRAFT_0191833, anticorps DDBDRAFT_0231037, anticorps DDB_0191833, anticorps DDB_0231037, anticorps AW545633, anticorps BTF2 p52, anticorps TFIIH, anticorps p44, anticorps p52, anticorps wu:fa04h09, anticorps zgc:77721, anticorps P52, anticorps TFB2, anticorps gtf2h4.1, anticorps discoidin domain receptor tyrosine kinase 1, anticorps general transcription factor IIH subunit 4, anticorps TFIIH subunit, anticorps valine--tRNA ligase, mitochondrial, anticorps general transcription factor II H, polypeptide 4, anticorps general transcription factor 2H subunit 4, anticorps general transcription factor IIH, polypeptide 4, anticorps general transcription factor IIH subunit 4 S homeolog, anticorps general transcription factor IIH, polypeptide 4, 52kDa, anticorps DDR1, anticorps GTF2H4, anticorps gtf2h4, anticorps LOC100351754, anticorps Gtf2h4, anticorps gtf2h4.S

Sujet:

Description: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.

Gene: GTF2H4

Poids moléculaire: 52 kDa

ID gène: 2968

UniProt: Q92759

Pathways: Réparation de l'ADN