IGHG1 anticorps

N° du produit ABIN6262500

Détail du produit anti-IGHG1 anticorps

Antigène: IGHG1 (Immunoglobulin Heavy Constant gamma 1 (G1m Marker) (IGHG1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IGHG1 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: IGHG1 Antibody detects endogenous levels of total IGHG1

Réactivité croisée: Humain

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human IGHG1

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C.Stable for 12 months from date of receipt

Date de péremption: 12 months

Détails sur IGHG1

Antigène: IGHG1 (Immunoglobulin Heavy Constant gamma 1 (G1m Marker) (IGHG1))

Autre désignation: IGHG1 (IGHG1 Produits)

Synonymes: anticorps RGD1359539, anticorps IgG1, anticorps Igh-4, anticorps VH7183, anticorps immunoglobulin heavy constant gamma 1, anticorps immunoglobulin heavy constant gamma 1 (G1m marker), anticorps Ighg1, anticorps IGHG1

Sujet:

Description: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).

Gene: IGHG1

UniProt: P01857