IL4 Receptor anticorps (N-Term)

N° du produit ABIN6262528

Cet anticorps anti-IL4 Receptor est un anticorps Lapin Polyclonal détectant IL4 Receptor dans WB, ELISA, IHC, IF et ICC. Adapté pour Humain et Souris.

Aperçu rapide pour IL4 Receptor anticorps (N-Term) (ABIN6262528)

Antigène: IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL4 Receptor est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-IL4 Receptor anticorps

Épitope: N-Term

Specificité: IL4R/CD124 Antibody detects endogenous levels of total IL4R/CD124.

Homologie: Horse,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human IL4R/CD124, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur IL4 Receptor

Antigène: IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))

Autre désignation: IL4R

Sujet:

Description: Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.

Gene: IL4R

Poids moléculaire: 89 kDa

ID gène: 3566

UniProt: P24394

Pathways: Signalistation JAK/STAT, Positive Regulation of Immune Effector Process