KCNJ10 anticorps (Internal Region)

N° du produit ABIN6262748

Détail du produit anti-KCNJ10 anticorps

Antigène: KCNJ10 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 10 (KCNJ10))

Épitope: Internal Region

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KCNJ10 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificité: KCNJ10 Antibody detects endogenous levels of total KCNJ10.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human KCNJ10, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur KCNJ10

Antigène: KCNJ10 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 10 (KCNJ10))

Autre désignation: KCNJ10 (KCNJ10 Produits)

Synonymes: anticorps kir1.2, anticorps kir4.1, anticorps birk-10, anticorps MGC145926, anticorps BIR10, anticorps BIRK-1, anticorps Kir1.2, anticorps Kir4.1, anticorps BIRK-10, anticorps KCNJ13-PEN, anticorps KIR1.2, anticorps KIR4.1, anticorps SESAME, anticorps potassium channel, inwardly rectifying subfamily J, member 10 L homeolog, anticorps potassium voltage-gated channel subfamily J member 10, anticorps potassium channel, inwardly rectifying subfamily J, member 10, anticorps potassium inwardly-rectifying channel, subfamily J, member 10, anticorps kcnj10.L, anticorps KCNJ10, anticorps kcnj10, anticorps Kcnj10

Sujet:

Description: May be responsible for potassium buffering action of glial cells in the brain. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium, as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium (By similarity). In the kidney, together with KCNJ16, mediates basolateral K+ recycling in distal tubules, this process is critical for Na+ reabsorption at the tubules.

Gene: KCNJ10

Poids moléculaire: 43 kDa

ID gène: 3766

UniProt: P78508

Pathways: Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity