MAGED1 anticorps (Internal Region)

N° du produit ABIN6263077

Détail du produit anti-MAGED1 anticorps

Antigène: MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAGED1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificité: MAGED1 Antibody detects endogenous levels of total MAGED1.

Homologie: Pig,Bovine,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human MAGED1, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur MAGED1

Antigène: MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))

Autre désignation: MAGED1 (MAGED1 Produits)

Synonymes: anticorps MAGED1, anticorps DLXIN-1, anticorps NRAGE, anticorps 2810433C11Rik, anticorps 5430405L04Rik, anticorps DXBwg1492e, anticorps Dlixin, anticorps Dlxin-1, anticorps Dlxin1, anticorps MAGE-D1, anticorps mFLJ00163, anticorps Nrage, anticorps MAGE family member D1, anticorps melanoma antigen family D, 1, anticorps melanoma antigen, family D, 1, anticorps MAGED1, anticorps Maged1

Sujet:

Description: Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Inhibits cell cycle progression, and facilitates NGFR-mediated apoptosis. May act as a regulator of the function of DLX family members. May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. Plays a role in the circadian rhythm regulation. May act as RORA co-regulator, modulating the expression of core clock genes such as ARNTL/BMAL1 and NFIL3, induced, or NR1D1, repressed.

Gene: MAGED1

Poids moléculaire: 86kDa

ID gène: 9500

UniProt: Q9Y5V3

Pathways: Neurotrophin Signaling Pathway