MAGT1 anticorps (Internal Region)

N° du produit ABIN6263082

Détail du produit anti-MAGT1 anticorps

Antigène: MAGT1 (Magnesium Transporter 1 (MAGT1))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAGT1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificité: MAGT1 Antibody detects endogenous levels of total MAGT1.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human MAGT1, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur MAGT1

Antigène: MAGT1 (Magnesium Transporter 1 (MAGT1))

Autre désignation: MAGT1 (MAGT1 Produits)

Synonymes: anticorps IAP, anticorps MRX95, anticorps OST3B, anticorps PRO0756, anticorps XMEN, anticorps bA217H1.1, anticorps 2410001C15Rik, anticorps 2610529C04Rik, anticorps 2810482I07Rik, anticorps IAG2, anticorps Iag2, anticorps magnesium transporter 1, anticorps MAGT1, anticorps Magt1

Sujet:

Description: Acts as accessory component of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. Involved in N-glycosylation of STT3B-dependent substrates. Specifically required for the glycosylation of a subset of acceptor sites that are near cysteine residues, in this function seems to act redundantly with TUSC3. In its oxidized form proposed to form transient mixed disulfides with a glycoprotein substrate to facilitate access of STT3B to the unmodified acceptor site. Has also oxidoreductase-independent functions in the STT3B-containing OST complex possibly involving substrate recognition.

Gene: MAGT1

Poids moléculaire: 45-47 kDa

ID gène: 84061

UniProt: Q9H0U3

Pathways: Cell RedoxHomeostasis