PIP4K2A anticorps (Internal Region)

N° du produit ABIN6264229

Détail du produit anti-PIP4K2A anticorps

Antigène: PIP4K2A (Phosphatidylinositol-5-Phosphate 4-Kinase, Type II, alpha (PIP4K2A))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PIP4K2A est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: PIP4K2A Antibody detects endogenous levels of total PIP4K2A.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human PIP4K2A, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur PIP4K2A

Antigène: PIP4K2A (Phosphatidylinositol-5-Phosphate 4-Kinase, Type II, alpha (PIP4K2A))

Autre désignation: PIP4K2A (PIP4K2A Produits)

Synonymes: anticorps PI5P4KA, anticorps PIP5K2A, anticorps PIP5KII-alpha, anticorps PIP5KIIA, anticorps PIPK, anticorps AW742916, anticorps Pip5k2a, anticorps pipk, anticorps pi5p4ka, anticorps pip5k2a, anticorps pip5kiia, anticorps pip4k2a, anticorps zgc:194746, anticorps zgc:194777, anticorps phosphatidylinositol-5-phosphate 4-kinase type 2 alpha, anticorps phosphatidylinositol-5-phosphate 4-kinase, type II, alpha, anticorps phosphatidylinositol-5-phosphate 4-kinase, type II, alpha S homeolog, anticorps phosphatidylinositol-5-phosphate 4-kinase, type II, alpha a, anticorps PIP4K2A, anticorps Pip4k2a, anticorps pip4k2a.S, anticorps pip4k2a, anticorps pip4k2aa

Sujet:

Description: Catalyzes the phosphorylation of phosphatidylinositol 5-phosphate (PtdIns5P) on the fourth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May exert its function by regulating the levels of PtdIns5P, which functions in the cytosol by increasing AKT activity and in the nucleus signals through ING2. May regulate the pool of cytosolic PtdIns5P in response to the activation of tyrosine phosphorylation. May negatively regulate insulin-stimulated glucose uptake by lowering the levels of PtdIns5P. May be involved in thrombopoiesis, and the terminal maturation of megakaryocytes and regulation of their size.

Gene: PIP4K2A

Poids moléculaire: 46 kDa

ID gène: 5305

UniProt: P48426

Pathways: Inositol Metabolic Process