TAF1 anticorps (Internal Region)

N° du produit ABIN6265434

Détail du produit anti-TAF1 anticorps

Antigène: TAF1 (TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 250kDa (TAF1))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TAF1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: TAF1 Antibody detects endogenous levels of total TAF1.

Homologie: Pig,Bovine,Horse,Rabbit,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human TAF1, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur TAF1

Antigène: TAF1 (TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 250kDa (TAF1))

Autre désignation: TAF1 (TAF1 Produits)

Synonymes: anticorps BG:DS00004.13, anticorps CG17603, anticorps Dmel\\CG17603, anticorps EfW1, anticorps SR3-5, anticorps TAF, anticorps TAF1, anticorps TAF200, anticorps TAF230, anticorps TAF250, anticorps TAF250/230, anticorps TAFII-250, anticorps TAFII250, anticorps TAF[II]250, anticorps TAF[[II]], anticorps TAF[[II]]230, anticorps TAF[[II]]250, anticorps TAF[[II]]250/230, anticorps TFIID, anticorps TFIID TAF250, anticorps Taf1p, anticorps Taf200, anticorps Taf230, anticorps Taf250, anticorps Taf[[II]]250, anticorps cel, anticorps cell, anticorps d230, anticorps dTAF230, anticorps dTAF250, anticorps dTAFII250, anticorps dTAF[[II]]230, anticorps dTAF[[II]]250, anticorps dmTAF1, anticorps dmTAF[[II]]230, anticorps l(3)84Ab, anticorps p230, anticorps 250kDa, anticorps AU015687, anticorps B430306D02Rik, anticorps Ccg-1, anticorps Ccg1, anticorps KAT4, anticorps N-TAF1, anticorps Taf2a, anticorps RGD1562050, anticorps BA2R, anticorps CCG1, anticorps CCGS, anticorps DYT3, anticorps DYT3/TAF1, anticorps NSCL2, anticorps OF, anticorps P250, anticorps TAF2A, anticorps XDP, anticorps TAF(II)250, anticorps p250, anticorps TBP-associated factor 1, anticorps TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa, anticorps transcription initiation factor TFIID subunit 1, anticorps transcription initiation factor TFIID, subunit TAF1, anticorps TATA-box binding protein associated factor 1, anticorps Taf1, anticorps TAF1, anticorps LOC5567420, anticorps CpipJ_CPIJ003658, anticorps TAF11.1, anticorps HAF1501, anticorps HAF1502, anticorps LOC100457071

Sujet:

Description: Largest component and core scaffold of the TFIID basal transcription factor complex (PubMed:25412659, PubMed:27007846). Contains novel N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Phosphorylates TP53 on 'Thr-55' which leads to MDM2-mediated degradation of TP53. Phosphorylates GTF2A1 and GTF2F1 on Ser residues. Possesses DNA-binding activity (PubMed:25412659). Essential for progression of the G1 phase of the cell cycle (PubMed:11278496, PubMed:15053879, PubMed:2038334, PubMed:8450888, PubMed:8625415, PubMed:9660973, PubMed:9858607). Exhibits histone acetyltransferase activity towards histones H3 and H4 (PubMed:15870300).

Gene: TAF1

Poids moléculaire: 212kDa

ID gène: 6872

UniProt: P21675