TSC22D3 anticorps (Internal Region)

N° du produit ABIN6265764

Détail du produit anti-TSC22D3 anticorps

Antigène: TSC22D3 (TSC22 Domain Family, Member 3 (TSC22D3))

Épitope: Internal Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TSC22D3 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: TSC-22R Antibody detects endogenous levels of total TSC-22R.

Homologie: Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human TSC-22R, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur TSC22D3

Antigène: TSC22D3 (TSC22 Domain Family, Member 3 (TSC22D3))

Autre désignation: TSC22D3 (TSC22D3 Produits)

Synonymes: anticorps dsipi, anticorps MGC53285, anticorps zgc:65831, anticorps zgc:77028, anticorps TSC22D3, anticorps GILZ, anticorps gilz, anticorps tsc-22r, anticorps DIP, anticorps DSIPI, anticorps TSC-22R, anticorps hDIP, anticorps Dsip1, anticorps Gilz, anticorps Tilz3, anticorps Dsipi, anticorps DSIP, anticorps TSC22 domain family member 3 L homeolog, anticorps TSC22 domain family, member 3, anticorps TSC22 domain family member 3, anticorps tsc22d3.L, anticorps tsc22d3, anticorps TSC22D3, anticorps Tsc22d3

Sujet:

Description: Protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11. In macrophages, plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10. In T-cells, inhibits anti-CD3-induced NFKB1 nuclear translocation. In vitro, suppresses AP1 and NFKB1 DNA-binding activities (By similarity). Isoform 1 inhibits myogenic differentiation and mediates anti-myogenic effects of glucocorticoids by binding and regulating MYOD1 and HDAC1 transcriptional activity resulting in reduced expression of MYOG (By similarity).

Gene: TSC22D3

Poids moléculaire: 15 kDa

ID gène: 1831

UniProt: Q99576