CEP290 anticorps (Internal Region)

N° du produit ABIN6284993

Détail du produit anti-CEP290 anticorps

Antigène: CEP290 (Centrosomal Protein 290kDa (CEP290))

Épitope: AA 740-820, Internal Region

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CEP290 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Fonction: CEP290 is a protein encoded by the CEP290 gene which is approximately 290,3 kDa. CEP290 is localised to the cytoplasm. It is involved in regulation of PLK1 activity at G2/M transition, innate immune system and mitotic cell cycle. It is a protein with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. It is involved in the early and late steps of cilia formation. CEP290 is ubiquitously expressed with stronger expression in the placenta. Mutations in the CEP290 gene may result in Joubert syndrome. STJ92224 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of CEP290 protein.

Specificité: CEP290 Polyclonal Antibody detects endogenous levels of CEP290 protein.

Attributs du produit: Rabbit polyclonal to CEP290.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human CEP290

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000
ELISA 1:20000

Commentaires:

Ubiquitous. Expressed strongly in placenta and weakly in brain.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C, and avoid repeat freeze-thaw cycles.

Détails sur CEP290

Antigène: CEP290 (Centrosomal Protein 290kDa (CEP290))

Autre désignation: CEP290 (CEP290 Produits)

Synonymes: anticorps ct87, anticorps mks4, anticorps rd16, anticorps bbs14, anticorps jbts5, anticorps jbts6, anticorps lca10, anticorps nphp6, anticorps slsn6, anticorps sh11ag, anticorps MGC81471, anticorps 3h11ag, anticorps RGD1311640, anticorps BC004690, anticorps Nphp6, anticorps b2b1454Clo, anticorps b2b1752Clo, anticorps im:7145703, anticorps im:7147820, anticorps 3H11Ag, anticorps BBS14, anticorps CT87, anticorps JBTS5, anticorps LCA10, anticorps MKS4, anticorps NPHP6, anticorps POC3, anticorps SLSN6, anticorps centrosomal protein 290, anticorps centrosomal protein 290 L homeolog, anticorps centrosomal protein 290kDa, anticorps CEP290, anticorps cep290.L, anticorps cep290, anticorps Cep290

Poids moléculaire: 290 kDa

ID gène: 80184

UniProt: O15078

Pathways: cAMP Metabolic Process, M Phase