Vinculin anticorps (AA 760-840)
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- Antigène Voir toutes Vinculin (VCL) Anticorps
- Vinculin (VCL)
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Épitope
- AA 760-840
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Vinculin est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Fonction
- Vinculin is a protein encoded by the VCL gene which is approximately 123,7 kDa. Vinculin is localised to the cell membrane. It is involved in RET signalling, signalling by moderate kinase activity BRAF mutants and focal adhesion. It is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. It may also play important roles in cell morphology and locomotion. Vinculin is expressed in the muscles. Mutations in the VCL gene may result in cardiomyopathy. STJ96247 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Vinculin protein.
- Specificité
- Vinculin Polyclonal Antibody detects endogenous levels of Vinculin protein.
- Attributs du produit
- Rabbit polyclonal to Vinculin.
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogène
- Synthesized peptide derived from human Vinculin around the non-phosphorylation site of Y821.
- Isotype
- IgG
- Top Product
- Discover our top product VCL Anticorps primaire
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- Indications d'application
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WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:10000 - Commentaires
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Metavinculin is muscle-specific.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- Antigène
- Vinculin (VCL)
- Autre désignation
- Vinculin (VCL Produits)
- Synonymes
- anticorps CMD1W, anticorps CMH15, anticorps MV, anticorps MVCL, anticorps VCL, anticorps im:6902790, anticorps hm:zehn2160, anticorps DDBDRAFT_0186762, anticorps DDBDRAFT_0232320, anticorps DDB_0186762, anticorps DDB_0232320, anticorps 9430097D22, anticorps AA571387, anticorps AI462105, anticorps AW545629, anticorps CG3299, anticorps CT11081, anticorps Dmel\\CG3299, anticorps Dmvincp, anticorps EG:103B4.1, anticorps Vin, anticorps Vin2EF, anticorps vinc, anticorps LOC100228062, anticorps vcl-A, anticorps vinculin, anticorps vinculin a, anticorps vinculin A, anticorps Vinculin, anticorps vinculin S homeolog, anticorps VCL, anticorps vcla, anticorps vinA, anticorps Vcl, anticorps Vinc, anticorps CpipJ_CPIJ013873, anticorps Bm1_37935, anticorps vcl, anticorps vcl.S
- Poids moléculaire
- 123 kDa
- ID gène
- 7414
- UniProt
- P18206
- Pathways
- Cell-Cell Junction Organization, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2
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