EGR2 anticorps (C-Term)

N° du produit ABIN6286258

Détail du produit anti-EGR2 anticorps

Antigène: EGR2 (Early Growth Response 2 (EGR2))

Épitope: AA 340-420, C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EGR2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Egr-2 is a protein encoded by the EGR2 gene which is approximately 50,3 kDa. Egr-2 is localised to the nucleus and is involved in toll-like receptor signalling pathway, HTLV-I infection, viral carcinogenesis and developmental biology. It is a sequence-specific DNA-binding transcription factor, it binds to two specific DNA sites located in the promoter region of HOXA4. It is also an E3 SUMO-protein ligase, helping SUMO1 conjugate to its coregulators NAB1 and NAB2, whose sumoylation down-regulates EGR2 own transcriptional activity. Egr-2 is expressed in the cells of the nervous system. Mutations in the EGR2 gene may result in congenital hypomyelinatingand Charcot-Marie-tooth disease. STJ92863 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. This antibody binds to endogenous Egr-2.

Specificité: Egr-2 Polyclonal Antibody detects endogenous levels of Egr-2 protein.

Attributs du produit: Rabbit polyclonal to Egr-2.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human Egr-2

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000

Commentaires:

Detected in neutrophils (at protein level).

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C, and avoid repeat freeze-thaw cycles.

Détails sur EGR2

Antigène: EGR2 (Early Growth Response 2 (EGR2))

Autre désignation: Egr-2 (EGR2 Produits)

Synonymes: anticorps AT591, anticorps CMT1D, anticorps CMT4E, anticorps KROX20, anticorps Egr-2, anticorps Krox-20, anticorps Krox20, anticorps NGF1-B, anticorps Zfp-25, anticorps Zfp-6, anticorps KRX-20, anticorps cb427, anticorps egr2, anticorps id:ibd5073, anticorps krox20, anticorps krx20, anticorps wu:fb71h10, anticorps zgc:92210, anticorps frb35, anticorps early growth response 2, anticorps early growth response 2b, anticorps early growth response 2a, anticorps EGR2, anticorps Egr2, anticorps egr2b, anticorps egr2a

Poids moléculaire: 50 kDa

ID gène: 1958

UniProt: P18146