YWHAB/YWHAZ anticorps (pSer184, pSer186)

N° du produit ABIN6287849

Détail du produit anti-YWHAB/YWHAZ anticorps

Antigène: YWHAB/YWHAZ (14-3-3 beta/zeta (YWHAB/YWHAZ))

Épitope: AA 120-200, pSer184, pSer186

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp YWHAB/YWHAZ est non-conjugé

Application: Western Blotting (WB), ELISA

Fonction: 14-3-3 β/ζ is a protein encoded by the YWHAZ gene which is approximately 27,7 kDa. 14-3-3 β/ζ is localised to the cytoplasm and melanosome. It is involved in the activation of cAMP-dependent PKA, development slit-robo signalling and activation of BH3-only proteins. It is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signalling pathways. It binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. 14-3-3 β/ζ is expressed in the nervous system, intestine, skin, blood and eye. STJ90562 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This primary antibody specifically binds to endogenous 14-3-3 β/ζ protein which only binds about S184/186 when S184/186 is phosphorylated.

Specificité: Phospho-14-3-3 β/ζ (S184/186) Polyclonal Antibody detects endogenous levels of 14-3-3 β/ζ protein only when phosphorylated at S184/186.

Attributs du produit: Rabbit polyclonal to Phospho-14-3-3 β/ζ (S184/186).

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human 14-3-3 beta/zeta around the phosphorylation site of S184/186.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000
ELISA 1:5000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C, and avoid repeat freeze-thaw cycles.

Détails sur YWHAB/YWHAZ

Antigène: YWHAB/YWHAZ (14-3-3 beta/zeta (YWHAB/YWHAZ))

Autre désignation: 14-3-3 beta/zeta (YWHAB/YWHAZ Produits)

Synonymes: anticorps 14-3-3z, anticorps 14-3-3zeta, anticorps kcip-1, anticorps ywhaq, anticorps Ywhaz, anticorps ACYPI003154, anticorps 1433z, anticorps tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta, anticorps 14-3-3 protein zeta, anticorps ywhaz, anticorps 14-3-3zeta, anticorps YWHAZ, anticorps 1433z

Poids moléculaire: 28 kDa

ID gène: 7534

UniProt: P63104