TUBB2A anticorps

N° du produit ABIN6288905

Détail du produit anti-TUBB2A anticorps

Antigène: TUBB2A (Tubulin, beta 2A (TUBB2A))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TUBB2A est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Fonction: β II tubulin is a protein encoded by the TUBB2A gene which is approximately 49,9 kDa. β II tubulin is localised to the cytoplasm and cytoskeleton. It is involved in Sertoli-Sertoli cell junction dynamics, development Slit-Robo signalling and the GPCR pathway. Tubulin is the major constituent of microtubules. Microtubules are key participants in processes such as mitosis and intracellular transport and are composed of heterodimers of alpha- and beta-tubulins. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. β II tubulin is expressed in the nervous system, eye, skin and lung. Mutations in the TUBB2A gene may result in lung mucoepidermoid carcinoma. STJ97053 was developed from clone Mix and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. The antibody detects endogenous β II tubulin protein.

Specificité: The antibody detects endogenous β II tubulin protein.

Attributs du produit: Mouse monoclonal to β II tubulin.

Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Immunogène: Synthetic Peptide

Clone: Mix

Isotype: IgG1

Information d'application

Indications d'application: WB 1:50000-100000
IP 1:200

Commentaires:

High expression in brain, where it represents 30% of all beta-tubulins.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C, and avoid repeat freeze-thaw cycles.

Détails sur TUBB2A

Antigène: TUBB2A (Tubulin, beta 2A (TUBB2A))

Autre désignation: beta II tubulin (TUBB2A Produits)

Synonymes: anticorps TUBB, anticorps TUBB2, anticorps dJ40E16.7, anticorps M(beta)2, anticorps Tubb2, anticorps TUBB2A, anticorps tubb2a, anticorps zgc:112335, anticorps tubulin beta 2A class IIa, anticorps tubulin, beta 2A class IIA, anticorps tubulin beta-2A chain, anticorps tubulin, beta 2A class IIa, anticorps TUBB2A, anticorps Tubb2a, anticorps LOC478701, anticorps LOC100079040, anticorps LOC100349792, anticorps LOC100599614, anticorps tubb2

ID gène: 7280

UniProt: Q13885

Pathways: Dynamique des Microtubules, M Phase