Calpain 6 anticorps

N° du produit ABIN6290227

Détail du produit anti-Calpain 6 anticorps

Antigène: Calpain 6 (CAPN6)

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Calpain 6 est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: Recombinant protein of human CAPN6

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000

Commentaires:

Expressed only in placenta

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20C. Avoid freeze / thaw cycles.

Détails sur Calpain 6

Antigène: Calpain 6 (CAPN6)

Autre désignation: CAPN6 (CAPN6 Produits)

Synonymes: anticorps CAPN6, anticorps CANPX, anticorps CAPNX, anticorps CalpM, anticorps DJ914P14.1, anticorps calpain 6, anticorps CAPN6, anticorps Capn6

Sujet: Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is highly expressed in the placenta. Its C-terminal region lacks any homology to the calmodulin-like domain of other calpains. The protein lacks critical active site residues and thus is suggested to be proteolytically inactive. The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis.

Poids moléculaire: 74.576 kDa

ID gène: 827

UniProt: Q9Y6Q1