PEG3 anticorps

N° du produit ABIN6290778

Détail du produit anti-PEG3 anticorps

Antigène: PEG3 (Paternally Expressed 3 (PEG3))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PEG3 est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: Recombinant protein of human PEG3

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000

Commentaires:

Brain, glial cells, astrocytes, embryo, placenta, testis, ovary and uterus, In the placenta it is found in the layer of villous cytotrophoblast cells while in the ovary it is found in the cells of the ovarian stroma including the thecal layers around the follicles, Expression is highly repressed in glioma cell lines

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20C. Avoid freeze / thaw cycles.

Détails sur PEG3

Antigène: PEG3 (Paternally Expressed 3 (PEG3))

Autre désignation: PEG3 (PEG3 Produits)

Synonymes: anticorps PW1, anticorps ZKSCAN22, anticorps ZNF904, anticorps ZSCAN24, anticorps AL022617, anticorps ASF-1, anticorps End4, anticorps Gcap4, anticorps Pw1, anticorps Zfp102, anticorps mKIAA0287, anticorps PEG3, anticorps paternally expressed 3, anticorps paternally-expressed gene 3 protein, anticorps PEG3, anticorps Peg3, anticorps LOC100448879

Sujet: In human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5' exons and a common promoter and both genes are paternally expressed (PMID:15203203). Alternative splicing events connect their shared 5' exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. In contrast, in other mammals ZIM2 does not undergo imprinting and, in mouse, cow, and likely other mammals as well, the ZIM2 and PEG3 genes do not share exons. Human PEG3 protein belongs to the Kruppel C2H2-type zinc finger protein family. PEG3 may play a role in cell proliferation and p53-mediated apoptosis. PEG3 has also shown tumor suppressor activity and tumorigenesis in glioma and ovarian cells. Alternative splicing of this PEG3 gene results in multiple transcript variants encoding distinct isoforms.

Poids moléculaire: 180.827 kDa

ID gène: 5178

UniProt: Q9GZU2