APOBEC3A anticorps
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- Antigène Voir toutes APOBEC3A Anticorps
- APOBEC3A (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3A (APOBEC3A))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp APOBEC3A est non-conjugé
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Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogène
- Recombinant protein of human APOBEC3A
- Isotype
- IgG
- Top Product
- Discover our top product APOBEC3A Anticorps primaire
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- Indications d'application
- WB 1:200 - 1:500
- Commentaires
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Expressed in peripheral leukocytes with higher expression in CD14-positive phagocytic cells, Highly expressed in keratinocytes and in periphery blood monocytes, Also detected in non-lymphoid tissues including lung and adipose tissues, Found at high levels in colorectal adenocarcinoma, Burkitt's lymphoma and chronic myelogenous leukemia
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20C. Avoid freeze / thaw cycles.
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- Antigène
- APOBEC3A (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3A (APOBEC3A))
- Autre désignation
- APOBEC3A (APOBEC3A Produits)
- Synonymes
- anticorps A3A, anticorps ARP3, anticorps PHRBN, anticorps bK150C2.1, anticorps APOBEC3A, anticorps APOBEC3Z1, anticorps apolipoprotein B mRNA editing enzyme catalytic subunit 3A, anticorps apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A, anticorps apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3Z1, anticorps similar to ARP10 protein, anticorps APOBEC3A, anticorps APOBEC3Z1
- Sujet
- This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. The protein encoded by this gene lacks the zinc binding activity of other family members. The protein plays a role in immunity, by restricting transmission of foreign DNA such as viruses. One mechanism of foreign DNA restriction is deamination of foreign double-stranded DNA cytidines to uridines, which leads to DNA degradation. However, other mechanisms are also thought to be involved, as anti-viral effect is not dependent on deaminase activity. Two transcript variants encoding different isoforms have been found for this gene.
- Poids moléculaire
- 23.012 kDa
- ID gène
- 100913187
- UniProt
- P31941
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