DNAJA3 anticorps

N° du produit ABIN6292022

Détail du produit anti-DNAJA3 anticorps

Antigène: DNAJA3 (DnaJ (Hsp40) Homolog, Subfamily A, Member 3 (DNAJA3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DNAJA3 est non-conjugé

Application: Immunofluorescence (IF)

Purification: Affinity purification

Immunogène: Recombinant protein of human DNAJA3

Isotype: IgG

Information d'application

Indications d'application: IF 1:50 - 1:200

Commentaires:

Widely expressed with highest levels in heart, liver, lung and skeletal muscles, Also expressed in keratinocytes

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20C. Avoid freeze / thaw cycles.

Détails sur DNAJA3

Antigène: DNAJA3 (DnaJ (Hsp40) Homolog, Subfamily A, Member 3 (DNAJA3))

Autre désignation: DNAJA3 (DNAJA3 Produits)

Synonymes: anticorps Tid-1, anticorps 1200003J13Rik, anticorps 1810053A11Rik, anticorps C81173, anticorps Tid1l, anticorps HCA57, anticorps TID1, anticorps hTID-1, anticorps DnaJ heat shock protein family (Hsp40) member A3, anticorps Dnaja3, anticorps DNAJA3

Sujet: This gene encodes a member of the DNAJ/Hsp40 protein family. DNAJ/Hsp40 proteins stimulate the ATPase activity of Hsp70 chaperones and play critical roles in protein folding, degradation, and multimeric complex assembly. The encoded protein is localized to mitochondria and mediates several cellular processes including proliferation, survival and apoptotic signal transduction. The encoded protein also plays a critical role in tumor suppression through interactions with oncogenic proteins including ErbB2 and the p53 tumor suppressor protein. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Poids moléculaire: 52.489 kDa

ID gène: 9093

UniProt: Q96EY1

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity