SKIL anticorps

N° du produit ABIN6292273

Détail du produit anti-SKIL anticorps

Antigène: SKIL (SKI-Like Oncogene (SKIL))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SKIL est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: Recombinant protein of human SKIL

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000

Commentaires:

Isoform SNON and isoform SNOA are widely expressed, Highest expression is found in skeletal muscle, followed by placenta and lung, Lowest expression in heart, brain and pancreas, Isoform SNOI expression is restricted to skeletal muscle

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20C. Avoid freeze / thaw cycles.

Détails sur SKIL

Antigène: SKIL (SKI-Like Oncogene (SKIL))

Autre désignation: SKIL (SKIL Produits)

Synonymes: anticorps SNO, anticorps SnoA, anticorps SnoI, anticorps SnoN, anticorps Skir, anticorps Sno, anticorps SKIL, anticorps DKFZp459L122, anticorps sno, anticorps zgc:193698, anticorps SKI like proto-oncogene, anticorps SKI-like proto-oncogene, anticorps ski-like protein, anticorps SKI-like, anticorps SKI-like proto-oncogene b, anticorps SKIL, anticorps Skil, anticorps LOC100010058, anticorps skil, anticorps skilb

Sujet: The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene.

Poids moléculaire: 76.976 kDa

ID gène: 6498

UniProt: P12757

Pathways: Positive Regulation of Response to DNA Damage Stimulus