TIRAP anticorps
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- Antigène Voir toutes TIRAP Anticorps
- TIRAP (Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TIRAP est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Purification
- Affinity purification
- Immunogène
- Recombinant protein of human TIRAP
- Isotype
- IgG
- Top Product
- Discover our top product TIRAP Anticorps primaire
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- Indications d'application
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WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200 - Commentaires
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Highly expressed in liver, kidney, spleen, skeletal muscle and heart, Also detected in peripheral blood leukocytes, lung, placenta, small intestine, thymus, colon and brain
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20C. Avoid freeze / thaw cycles.
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- Antigène
- TIRAP (Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP))
- Autre désignation
- TIRAP (TIRAP Produits)
- Synonymes
- anticorps mal, anticorps wyatt, anticorps BACTS1, anticorps Mal, anticorps MyD88-2, anticorps AA407980, anticorps C130027E04Rik, anticorps Tlr4ap, anticorps Wyatt, anticorps toll-interleukin 1 receptor (TIR) domain containing adaptor protein, anticorps TIR domain containing adaptor protein, anticorps toll-interleukin 1 receptor (TIR) domain containing adaptor protein L homeolog, anticorps toll-interleukin 1 receptor (TIR) domain-containing adaptor protein, anticorps tirap, anticorps TIRAP, anticorps tirap.L, anticorps Tirap
- Sujet
- The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants, however, not all variants have been fully described.
- Poids moléculaire
- 23.883 kDa
- ID gène
- 114609
- UniProt
- P58753
- Pathways
- Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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