NECAB3 anticorps
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- Antigène Voir toutes NECAB3 Anticorps
- NECAB3 (N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NECAB3 est non-conjugé
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Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogène
- Recombinant protein of human NECAB3
- Isotype
- IgG
- Top Product
- Discover our top product NECAB3 Anticorps primaire
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- Indications d'application
- WB 1:200 - 1:2000
- Commentaires
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Strongly expressed in heart and skeletal muscle, moderately in brain and pancreas
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20C. Avoid freeze / thaw cycles.
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- Antigène
- NECAB3 (N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3))
- Autre désignation
- NECAB3 (NECAB3 Produits)
- Synonymes
- anticorps Apba2bp, anticorps APBA2BP, anticorps NECAB3, anticorps EFCBP3, anticorps NIP1, anticorps STIP3, anticorps SYTIP2, anticorps XB51, anticorps dJ63M2.4, anticorps dJ63M2.5, anticorps 2900010M17Rik, anticorps AI853434, anticorps Nip1, anticorps N-terminal EF-hand calcium binding protein 3, anticorps Necab3, anticorps NECAB3
- Sujet
- The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.
- Poids moléculaire
- 44.35 kDa
- ID gène
- 63941
- UniProt
- Q96P71
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