ANKHD1 anticorps

N° du produit ABIN6292808

Détail du produit anti-ANKHD1 anticorps

Antigène: ANKHD1 (Ankyrin Repeat and KH Domain Containing 1 (ANKHD1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ANKHD1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogène: Recombinant protein of human ANKHD1

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000
IHC 1:50 - 1:200

Commentaires:

Ubiquitous with high expression in cervix, spleen and brain, Expressed in hematopoietic cells with increased expression in leukemia cells, Isoform 2 is highly expressed in spleen with almost no expression in muscle and brain

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20C. Avoid freeze / thaw cycles.

Détails sur ANKHD1

Antigène: ANKHD1 (Ankyrin Repeat and KH Domain Containing 1 (ANKHD1))

Autre désignation: ANKHD1 (ANKHD1 Produits)

Synonymes: anticorps 1110004O12Rik, anticorps 4933432B13Rik, anticorps 9130019P20Rik, anticorps A530027J04Rik, anticorps A630021B20Rik, anticorps AA571404, anticorps Mask, anticorps mFLJ00246, anticorps mKIAA1085, anticorps MASK, anticorps VBARP, anticorps ankyrin repeat and KH domain containing 1, anticorps Ankhd1, anticorps ANKHD1

Sujet: This gene encodes a protein with multiple ankyrin repeat domains and a single KH-domain. The protein is thought to function as a scaffolding protein, and it may be involved in the regulation of caspases and thereby play an antiapoptotic role in cell survival. Alternative splicing results in multiple transcript variants, one of which generates a fusion transcript (MASK-BP3) with the downstream eIF4E-binding protein 3 (EIF4EBP3) gene, resulting in a protein comprised of the ANKHD1 sequence for the majority of the protein and a different C-terminus due to an alternate reading frame for the EIF4EBP3 segments.

Poids moléculaire: 269.458 kDa

ID gène: 404734

UniProt: Q8IWZ3