ITGB3BP anticorps

N° du produit ABIN6293028

Détail du produit anti-ITGB3BP anticorps

Antigène: ITGB3BP (Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ITGB3BP est non-conjugé

Application: Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogène: Recombinant protein of human ITGB3BP

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50 - 1:200

Commentaires:

Widely expressed, Expressed in spleen, thymus, prostate, ovary, small intestine and white blood cells, Highly expressed in testis and colon, Isoform 4 is expressed in platelets, lymphocytes and granulocytes

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20C. Avoid freeze / thaw cycles.

Détails sur ITGB3BP

Antigène: ITGB3BP (Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP))

Autre désignation: ITGB3BP (ITGB3BP Produits)

Synonymes: anticorps CENP-R, anticorps CENPR, anticorps HSU37139, anticorps NRIF3, anticorps TAP20, anticorps 4930471O16Rik, anticorps AU022583, anticorps integrin subunit beta 3 binding protein, anticorps integrin beta 3 binding protein (beta3-endonexin), anticorps ITGB3BP, anticorps Itgb3bp

Sujet: This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.

Poids moléculaire: 20.194 kDa

ID gène: 23421

UniProt: Q13352

Pathways: Neurotrophin Signaling Pathway