RASD1 anticorps

N° du produit ABIN6293268

Détail du produit anti-RASD1 anticorps

Antigène: RASD1 (RAS, Dexamethasone-Induced 1 (RASD1))

Reactivité: Souris, Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RASD1 est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: Recombinant protein of human RASD1

Isotype: IgG

Information d'application

Indications d'application: WB 1:200 - 1:2000

Commentaires:

Expressed in a variety of tissues including heart, cardiovascular tissues, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, gastrointestinal and reproductive tissues

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20C. Avoid freeze / thaw cycles.

Détails sur RASD1

Antigène: RASD1 (RAS, Dexamethasone-Induced 1 (RASD1))

Autre désignation: RASD1 (RASD1 Produits)

Synonymes: anticorps AGS1, anticorps DEXRAS1, anticorps MGC:26290, anticorps Dexras1, anticorps ras related dexamethasone induced 1, anticorps RAS, dexamethasone-induced 1, anticorps RASD1, anticorps Rasd1

Sujet: This gene encodes a member of the Ras superfamily of small GTPases and is induced by dexamethasone. The encoded protein is an activator of G-protein signaling and acts as a direct nucleotide exchange factor for Gi-Go proteins. This protein interacts with the neuronal nitric oxide adaptor protein CAPON, and a nuclear adaptor protein FE65, which interacts with the Alzheimer's disease amyloid precursor protein. This gene may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. Epigenetic inactivation of this gene is closely correlated with resistance to dexamethasone in multiple myeloma cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 31.642 kDa

ID gène: 51655

UniProt: Q9Y272