COQ6 anticorps
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- Antigène Voir toutes COQ6 Anticorps
- COQ6 (Coenzyme Q6, Monooxygenase (COQ6))
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp COQ6 est non-conjugé
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Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogène
- Recombinant protein of human COQ6
- Isotype
- IgG
- Top Product
- Discover our top product COQ6 Anticorps primaire
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- Indications d'application
- WB 1:500 - 1:2000
- Commentaires
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Widely expressed
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20C. Avoid freeze / thaw cycles.
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- Antigène
- COQ6 (Coenzyme Q6, Monooxygenase (COQ6))
- Autre désignation
- COQ6 (COQ6 Produits)
- Synonymes
- anticorps CGI10, anticorps COQ10D6, anticorps 5930427M12Rik, anticorps AW742344, anticorps zgc:153379, anticorps coq6, anticorps coenzyme Q6, monooxygenase, anticorps coenzyme Q6 monooxygenase, anticorps Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial, anticorps coenzyme Q6 monooxygenase L homeolog, anticorps COQ6, anticorps Coq6, anticorps coq-6, anticorps coq6, anticorps coq6.L
- Sujet
- The protein encoded by this gene belongs to the ubiH/COQ6 family. It is an evolutionarily conserved monooxygenase required for the biosynthesis of coenzyme Q10 (or ubiquinone), which is an essential component of the mitochondrial electron transport chain, and one of the most potent lipophilic antioxidants implicated in the protection of cell damage by reactive oxygen species. Knockdown of this gene in mouse and zebrafish results in decreased growth due to increased apoptosis. Mutations in this gene are associated with autosomal recessive coenzyme Q10 deficiency-6 (COQ10D6), which manifests as nephrotic syndrome with sensorineural deafness. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
- Poids moléculaire
- 50.87 kDa
- ID gène
- 51004
- UniProt
- Q9Y2Z9
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