PTPN13 anticorps
-
- Antigène Voir toutes PTPN13 Anticorps
- PTPN13 (Protein tyrosine Phosphatase, Non-Receptor Type 13 (APO-1/CD95 (Fas)-Associated Phosphatase) (PTPN13))
-
Reactivité
- Humain, Souris
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp PTPN13 est non-conjugé
-
Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogène
- Recombinant protein of human PTPN13
- Isotype
- IgG
- Top Product
- Discover our top product PTPN13 Anticorps primaire
-
-
- Indications d'application
- WB 1:500 - 1:2000
- Commentaires
-
Present in most tissues with the exception of the liver and skeletal muscle, Most abundant in lung, kidney and fetal brain
- Restrictions
- For Research Use only
-
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20C. Avoid freeze / thaw cycles.
-
- Antigène
- PTPN13 (Protein tyrosine Phosphatase, Non-Receptor Type 13 (APO-1/CD95 (Fas)-Associated Phosphatase) (PTPN13))
- Autre désignation
- PTPN13 (PTPN13 Produits)
- Synonymes
- anticorps FAP-1, anticorps PNP1, anticorps PTP-BAS, anticorps PTP-BL, anticorps PTP1E, anticorps PTPL1, anticorps PTPLE, anticorps hPTP1E, anticorps PTPN13, anticorps AI324989, anticorps Ptpri, anticorps RIP, anticorps Ptp-bl, anticorps ptp, anticorps wu:fb50g04, anticorps zgc:162319, anticorps protein tyrosine phosphatase, non-receptor type 13, anticorps tyrosine-protein phosphatase non-receptor type 13, anticorps PTPN13, anticorps LOC100540743, anticorps ptpn13, anticorps Ptpn13
- Sujet
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large intracellular protein. It has a catalytic PTP domain at its C-terminus and two major structural domains: a region with five PDZ domains and a FERM domain that binds to plasma membrane and cytoskeletal elements. This PTP was found to interact with, and dephosphorylate, Fas receptor and IkappaBalpha through the PDZ domains. This suggests it has a role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathways. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported.
- Poids moléculaire
- 276.906 kDa
- ID gène
- 5783
- UniProt
- Q12923
-