WWOX anticorps

N° du produit ABIN6293667

Détail du produit anti-WWOX anticorps

Antigène: WWOX (WW Domain Containing Oxidoreductase (WWOX))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WWOX est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: Recombinant protein of human WWOX

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000 - 1:2000

Commentaires:

Widely expressed, Strongly expressed in testis, prostate, and ovary, Overexpressed in cancer cell lines, Isoform 5 and isoform 6 may only be expressed in tumor cell lines

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20C. Avoid freeze / thaw cycles.

Détails sur WWOX

Antigène: WWOX (WW Domain Containing Oxidoreductase (WWOX))

Autre désignation: WWOX (WWOX Produits)

Synonymes: anticorps CG7221, anticorps DmWWOX, anticorps Dmel\\CG7221, anticorps anon-EST:Posey177, anticorps GB11795, anticorps WWOX, anticorps D16S432E, anticorps FOR, anticorps FRA16D, anticorps HHCMA56, anticorps PRO0128, anticorps SDR41C1, anticorps WOX1, anticorps zgc:55975, anticorps 5330426P09Rik, anticorps 9030416C10Rik, anticorps WW domain containing oxidoreductase, anticorps WW domain-containing oxidoreductase, anticorps Wwox, anticorps LOC411815, anticorps WWOX, anticorps CpipJ_CPIJ004939, anticorps MCYG_01584, anticorps VDBG_05631, anticorps VDBG_01326, anticorps VDBG_06753, anticorps Tsp_03967, anticorps LOC100284583, anticorps wwox

Sujet: This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. This gene spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated with multiple types of cancer. Disruption of this gene is also associated with autosomal recessive spinocerebellar ataxia 12. Disruption of a similar gene in mouse results in impaired steroidogenesis, additionally suggesting a metabolic function for the protein. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 46.677 kDa

ID gène: 51741

UniProt: Q9NZC7