PES1 anticorps

N° du produit ABIN6293971

Détail du produit anti-PES1 anticorps

Antigène: PES1 (Pescadillo Ribosomal Biogenesis Factor 1 (PES1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PES1 est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: Recombinant protein of human PES1

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000

Commentaires:

Significant levels are detected in a variety of cancer cell lines, including glioblastoma, breast carcinoma, colon carcinoma and cervical carcinoma cells, Levels are abnormally elevated in malignant tumors of astrocytic origin

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20C. Avoid freeze / thaw cycles.

Détails sur PES1

Antigène: PES1 (Pescadillo Ribosomal Biogenesis Factor 1 (PES1))

Autre désignation: PES1 (PES1 Produits)

Synonymes: anticorps PES, anticorps pes, anticorps pes1, anticorps pescadillo ribosomal biogenesis factor 1, anticorps pescadillo ribosomal biogenesis factor 1 S homeolog, anticorps Pescadillo, anticorps PES1, anticorps Pes1, anticorps pes1.S, anticorps pesc

Sujet: This gene encodes a nuclear protein that contains a breast cancer associated gene 1 (BRCA1) C-terminal interaction domain. The encoded protein interacts with BOP1 and WDR12 to form the PeBoW complex, which plays a critical role in cell proliferation via pre-rRNA processing and 60S ribosomal subunit maturation. Expression of this gene may play an important role in breast cancer proliferation and tumorigenicity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the long arm of chromosome 4 and the short arm of chromosome 9.

Poids moléculaire: 68.003 kDa

ID gène: 23481

UniProt: O00541