Proteoglycan 4 anticorps

N° du produit ABIN6294151

Détail du produit anti-Proteoglycan 4 anticorps

Antigène: Proteoglycan 4 (PRG4)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Proteoglycan 4 est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: Recombinant protein of human PRG4

Isotype: IgG

Information d'application

Indications d'application: WB 1:200 - 1:2000

Commentaires:

Highly expressed in synovial tissue, cartilage and liver and weakly in heart and lung, Isoform B is expressed in kidney, lung, liver, heart and brain, Isoform C and isoform D are widely expressed

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20C. Avoid freeze / thaw cycles.

Détails sur Proteoglycan 4

Antigène: Proteoglycan 4 (PRG4)

Autre désignation: PRG4 (PRG4 Produits)

Synonymes: anticorps CACP, anticorps HAPO, anticorps JCAP, anticorps MSF, anticorps SZP, anticorps bG174L6.2, anticorps lubricin, anticorps prg4, anticorps si:dkey-97o5.3, anticorps zgc:122988, anticorps PRG4, anticorps DOL54, anticorps proteoglycan 4, anticorps proteoglycan 4b, anticorps proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein), anticorps PRG4, anticorps Prg4, anticorps prg4b

Sujet: The protein encoded by this gene is a large proteoglycan that is synthesized by chondrocytes located at the surface of articular cartilage and by some synovial lining cells. This protein contains both chondroitin sulfate and keratan sulfate glycosaminoglycans. It functions as a boundary lubricant at the cartilage surface and contributes to the elastic absorption and energy dissipation of synovial fluid. Mutations in this gene result in camptodactyly-arthropathy-coxa vara-pericarditis syndrome. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 151.077 kDa

ID gène: 10216

UniProt: Q92954