TRIM29 anticorps (AA 1-200)

N° du produit ABIN6294234

Cet anticorps anti-TRIM29 est un anticorps Souris Monoclonal détectant TRIM29 dans WB, IF et FACS. Adapté pour Humain.

Aperçu rapide pour TRIM29 anticorps (AA 1-200) (ABIN6294234)

Antigène: TRIM29 (Tripartite Motif Containing 29 (TRIM29))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TRIM29 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-TRIM29 anticorps

Épitope: AA 1-200

Fonction: Mouse anti-Human TRIM29 Antibody [Sodium Azide Free]

Specificité: Cytoplasmic & cell surface

Purification: A recombinant fragment (126 amino acid residues between aa 1-200) from the human protein was used as the immunogen for the TRIM29 antibody.

Immunogène: A recombinant fragment (126 amino acid residues between aa 1-200) from the human protein was used as the immunogen for the TRIM29 antibody.

Information d'application

Indications d'application: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur TRIM29

Antigène: TRIM29 (Tripartite Motif Containing 29 (TRIM29))

Autre désignation: Tripartite motif-containing protein 29

Sujet:

Target Description: It recognizes a 66 kDa protein, which is identified as Tripartite motif-containing protein 29 (TRIM29). It interacts with the intermediate filament protein vimentin, a substrate for the PKC family of protein kinases, and with hPKCI-1, an inhibitor of the PKCs. TRIM29 protein contains both zinc finger and leucine zipper motifs, suggesting that the it may form homodimers and possibly associate with DNA. High expression of TRIM29 has been reported in gastric cancer and pancreatic cancer, and correlates with enhanced tumor growth and lymph node metastasis. TRIM29 is also able to distinguish lung squamous cell carcinoma from lung adenocarcinoma with ~90 % positive accuracy, when used in a panel with TTF-1, p63, CK5/6, and Napsin-A antibodies.

Gene Symbol: TRIM29///ATDC

ID gène: 23650

UniProt: Q14134

Pathways: Signalisation p53, Apoptose, Réparation de l'ADN, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus