CD3 epsilon anticorps (Cytoplasmic Domain)

N° du produit ABIN6294325

Cet anticorps Souris Monoclonal détecte spécifiquement CD3 epsilon dans FACS, WB, IHC et IF. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Porc, Boeuf (Vache), Cheval, Lapin et Cobaye.

Aperçu rapide pour CD3 epsilon anticorps (Cytoplasmic Domain) (ABIN6294325)

Antigène: CD3 epsilon (CD3E)

Reactivité: Humain, Souris, Rat, Porc, Boeuf (Vache), Cheval, Lapin, Cobaye

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD3 epsilon est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-CD3 epsilon anticorps

Épitope: AA 156-168, Cytoplasmic Domain

Fonction: Mouse anti-Human/Mouse/Rat/Rabbit/Guinea pig/Pig/Horse/Cow CD3e Antibody [Sodium Azide Free]

Specificité: Cell surface and cytoplasmic

Purification: Amino acids 156-168 (cytoplasmic domain) from human CD3 epsilon chain were used as the immunogen for the CD3e antibody.

Immunogène: Amino acids 156-168 (cytoplasmic domain) from human CD3 epsilon chain were used as the immunogen for the CD3e antibody.

Information d'application

Indications d'application: WB: 1-2 μg/mL
IHC (FFPE): 1-2 μg/mL for 30 min at RT
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur CD3 epsilon

Antigène: CD3 epsilon (CD3E)

Autre désignation: T-cell surface glycoprotein CD3 epsilon chain

Sujet:

Target Description: Recognizes the epsilon chain of CD3, a protein which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28 kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms.

Gene Symbol: CD3E///T3E

ID gène: 916

UniProt: P07766

Pathways: TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway