CD3 epsilon anticorps

N° du produit ABIN6297680

L’anticorps Souris Monoclonal anti-CD3 epsilon a été validé pour FACS, IF, Func, Act et ProA. Il convient pour détecter CD3 epsilon dans des échantillons de Humain et Singe.

Aperçu rapide pour CD3 epsilon anticorps (ABIN6297680)

Antigène: CD3 epsilon (CD3E)

Reactivité: Humain, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD3 epsilon est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func), Activation (Act), Proliferation Assay (ProA)

Détail du produit anti-CD3 epsilon anticorps

Fonction: Mouse anti-Human/Monkey CD3e Antibody [Sodium Azide Free]

Specificité: Cell surface and cytoplasmic

Purification: Stimulated human leukocytes were used as the immunogen for the CD3e antibody.

Immunogène: Stimulated human leukocytes were used as the immunogen for the CD3e antibody.

Information d'application

Indications d'application: Functional Activity: Induce T cell activation and proliferation (Order SAF formulation)
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur CD3 epsilon

Antigène: CD3 epsilon (CD3E)

Autre désignation: T-cell surface glycoprotein CD3 epsilon chain

Sujet:

Target Description: Recognizes the epsilon-chain of CD3 (Workshop V, Code: CD03.09), which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28 kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms.

Gene Symbol: CD3E///T3E

ID gène: 916

UniProt: P07766

Pathways: TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway