TNF alpha anticorps (Biotin)

N° du produit ABIN6297805

Cet anticorps Souris Monoclonal détecte spécifiquement TNF alpha dans WB et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour TNF alpha anticorps (Biotin) (ABIN6297805)

Antigène: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TNF alpha est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA

Clone: 5H4-F10-E11

Détail du produit anti-TNF alpha anticorps (Biotin)

Fonction: Mouse anti-Human TNF alpha Biotinylated Antibody

Immunogène: This antibody was produced by fusion of mouse myeloma with B cells obtained from a mouse immunized with a recombinant protein immunogen. The IgG fraction of tissue culture supernatant was purified by Protein G/A affinity chromatography.

Isotype: IgG3

Information d'application

Indications d'application: ELISA (recommended dilution= 1:320,000), Western Blotting (recommended dilution= 1:1,000-5,000)

Restrictions: For Research Use only

Stockage

Reconstitution: A separate vial of dilution buffer is provided for reconstitution. The antibody is supplied lyophilized, originally containing PBS, without preservative stabilizers (e. g. sodium azide). The final amount is indicated on the shipping vial.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: -20°C

Détails sur TNF alpha

Antigène: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Autre désignation: TNF alpha

Sujet:

Target Description: TNF alpha is an  adipokine  involved in systemic  inflammation  and is a member of a group of cytokines that stimulate the  acute phase reaction. It is produced chiefly by activated  macrophages  (M1), although it can be produced by many other cell types such asCD4+ lymphocytes,  NK cells, neutrophils, mast cells, eosinophils, and neurons.

UniProt: P78536

Pathways: Signalisation NF-kappaB, Apoptose, Caspase Cascade in Apoptosis, Signalisation TLR, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome