SOCS1 anticorps (N-Term)

N° du produit ABIN630223

Cet anticorps Lapin Polyclonal détecte spécifiquement SOCS1 dans WB et IHC. Il présente une réactivité envers Humain, Souris, Rat et Chien.

Aperçu rapide pour SOCS1 anticorps (N-Term) (ABIN630223)

Antigène: SOCS1 (Suppressor of Cytokine Signaling 1 (SOCS1))

Reactivité: Humain, Souris, Rat, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOCS1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-SOCS1 anticorps

Épitope: N-Term

Specificité: SOCS1 antibody was raised against the N terminal of SOCS1

Purification: Purified

Immunogène: SOCS1 antibody was raised using the N terminal of SOCS1 corresponding to a region with amino acids RRPEPSSSSSSSPAAPARPRPCPAVPAPAPGDTHFRTFRSHADYRRITRA

Information d'application

Indications d'application: WB: 1.25 µg/mL, IHC: 4-8 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

SOCS1 Blocking Peptide, (ABIN5616330), is also available for use as a blocking control in assays to test for specificity of this SOCS1 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of SOCS1 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Détails sur SOCS1

Antigène: SOCS1 (Suppressor of Cytokine Signaling 1 (SOCS1))

Autre désignation: SOCS1

Sujet: SOCS1 is a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. SOCS1 functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of its gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.

Poids moléculaire: 23 kDa (MW of target protein)

Pathways: Signalistation JAK/STAT, Interferon-gamma Pathway, Signalisation TLR, Response to Growth Hormone Stimulus