NR0B2 anticorps (N-Term)
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- Antigène Voir toutes NR0B2 Anticorps
- NR0B2 (Nuclear Receptor Subfamily 0, Group B, Member 2 (NR0B2))
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Épitope
- N-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NR0B2 est non-conjugé
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Application
- Western Blotting (WB)
- Specificité
- NR0 B2 antibody was raised against the N terminal of NR0 2
- Purification
- Affinity purified
- Immunogène
- NR0 B2 antibody was raised using the N terminal of NR0 2 corresponding to a region with amino acids STSQPGACPCQGAASRPAILYALLSSSLKAVPRPRSRCLCRQHRPVQLCA
- Top Product
- Discover our top product NR0B2 Anticorps primaire
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- Indications d'application
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. - Commentaires
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NR0B2 Blocking Peptide, catalog no. 33R-8889, is also available for use as a blocking control in assays to test for specificity of this NR0B2 antibody
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of NR0 2 antibody in PBS
- Concentration
- Lot specific
- Buffer
- PBS
- Conseil sur la manipulation
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- Antigène
- NR0B2 (Nuclear Receptor Subfamily 0, Group B, Member 2 (NR0B2))
- Autre désignation
- NR0B2 (NR0B2 Produits)
- Synonymes
- anticorps SHP, anticorps SHP1, anticorps SHP-1, anticorps Shp1, anticorps Shp, anticorps NR0B2-A, anticorps Nr0b2, anticorps SHP-A, anticorps gb:bc058069, anticorps nuclear receptor subfamily 0 group B member 2, anticorps nuclear receptor subfamily 0, group B, member 2, anticorps nuclear receptor subfamily 0, group B, member 2a, anticorps NR0B2, anticorps Nr0b2, anticorps nr0b2a
- Sujet
- NR0B2 is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. It is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors, inhibiting their ligand-dependent transcriptional activation. In addition, interaction with estrogen receptors has been demonstrated, leading to inhibition of function.
- Poids moléculaire
- 28 kDa (MW of target protein)
- Pathways
- Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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