NDFIP2 anticorps (Middle Region)
Aperçu rapide pour NDFIP2 anticorps (Middle Region) (ABIN633059)
Antigène
Voir toutes NDFIP2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- Middle Region
-
Specificité
- NDFIP2 antibody was raised against the middle region of NDFIP2
-
Purification
- Affinity purified
-
Immunogène
- NDFIP2 antibody was raised using the middle region of NDFIP2 corresponding to a region with amino acids SFCITNTIAGRYGAICGFGLSLIKWILIVRFSDYFTGYFNGQYWLWWIFL
-
-
-
-
Indications d'application
-
WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
Commentaires
-
NDFIP2 Blocking Peptide, (ABIN5614937), is also available for use as a blocking control in assays to test for specificity of this NDFIP2 antibody
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of NDFIP2 antibody in PBS
-
Concentration
- Lot specific
-
Buffer
- PBS
-
Conseil sur la manipulation
-
Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Stock
- 4 °C/-20 °C
-
Stockage commentaire
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
-
-
- NDFIP2 (Nedd4 Family Interacting Protein 2 (NDFIP2))
-
Autre désignation
- NDFIP2
-
Sujet
- NDFIP2 activates HECT domain-containing E3 ubiquitin-protein ligases, including ITCH, NEDD4, NEDD4L, SMURF2, WWP1 and WWP2, and consequently modulates the stability of their targets. As a result, NDFIP2 may control many cellular processes. NDFIP2 recruits ITCH, NEDD4 and SMURF2 to endosomal membranes. NDFIP2 may modulate EGFR signaling.
-
Poids moléculaire
- 36 kDa (MW of target protein)
-
Pathways
- Negative Regulation of Transporter Activity, SARS-CoV-2 Protein Interactome
Antigène
-