Presenilin 2 anticorps
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- Antigène Voir toutes Presenilin 2 (PSEN2) Anticorps
- Presenilin 2 (PSEN2) (Presenilin 2 (Alzheimer Disease 4) (PSEN2))
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Reactivité
- Mammifères
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Hôte
- Chèvre
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Presenilin 2 est non-conjugé
- Application
- Veuillez nous consulter SVP
- Purification
- Purified
- Top Product
- Discover our top product PSEN2 Anticorps primaire
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- Indications d'application
- Optimal conditions should be determined byt he investigator.
- Restrictions
- For Research Use only
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- Concentration
- Lot specific
- Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
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- Antigène
- Presenilin 2 (PSEN2) (Presenilin 2 (Alzheimer Disease 4) (PSEN2))
- Autre désignation
- Presenilin 2 (PSEN2 Produits)
- Synonymes
- anticorps AD3L, anticorps AD4, anticorps CMD1V, anticorps PS2, anticorps STM2, anticorps ALG-3, anticorps Ad4h, anticorps Alg3, anticorps PS-2, anticorps Psnl2, anticorps pre2, anticorps zf-PS2, anticorps PSNL2, anticorps PSEN2, anticorps ad4, anticorps ps2, anticorps ad3l, anticorps stm2, anticorps Ps2, anticorps presenilin 2, anticorps presenilin 2 S homeolog, anticorps presenilin 2 (Alzheimer disease 4), anticorps trefoil factor 1, anticorps PSEN2, anticorps Psen2, anticorps psen2, anticorps psen2.S, anticorps Tff1
- Sujet
- Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1, PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP.
- Pathways
- Signalisation Notch, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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