TNF alpha anticorps (Biotin)
Aperçu rapide pour TNF alpha anticorps (Biotin) (ABIN639287)
Antigène
Voir toutes TNF alpha AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- Mouse Anti-Bovine TNF-alpha [+Biotin]
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Specificité
- This product recognizes bovine TNF alpha, a 17.5kDa cytokine, expressed by many different stimulated cell types including monocytes, macrophages, endothelial cells, fibroblasts and both T and B-lymphocytes. The production of TNF alpha is induced by a variety of factors, dependant upon cell type and includes bacterial toxins, IL-1, PDGF, IFN-beta, NGF, Oncostatin M and viral infections. The presence of TNF alpha is responsible for diverse immunomodulatory, anti-tumour and toxic effects and under certain conditions is also capable of self-stimulation and inhibition. This biotin conjugate may be used as a detection antibody in ELISA assays for bovine TNF alpha in combination with DS-MB-02436 as capture reagent.
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Réactivité croisée
- Mouton
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Attributs du produit
- Cytokines/Chemokines/Growth Factors/Receptors
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Immunogène
- Recombinant bovine TNF alpha
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Isotype
- IgG2a
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Indications d'application
- ELISA (dilution: 1/10 , 1/100), Flow Cytometry
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Restrictions
- For Research Use only
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Concentration
- IgG concentration 1.0 mg/ml
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Buffer
- Phosphate buffered saline pH7.4
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- -20°C
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- TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
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Autre désignation
- Tumor Necrosis Factor alpha (TNF-alpha)
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Pathways
- Signalisation NF-kappaB, Apoptose, Caspase Cascade in Apoptosis, Signalisation TLR, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome
Antigène
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