OLR1 anticorps (Soluble)

N° du produit ABIN639899

Détail du produit anti-OLR1 anticorps

Antigène: OLR1 (Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1))

Épitope: Soluble

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp OLR1 est non-conjugé

Application: Western Blotting (WB), ELISA

Fonction: Mouse Anti-Human LOX-1 (soluble)

Specificité: DS-MB-03380 recognizes the lectin-like oxidised low-density lipoprotein (LDL) receptor (LOX-1), a 31kDa protein of the C-type lectin superfamily. This receptor mediates the recognition, internalization and degradation of oxidized LDL. It is a Type II membrane protein with a typical C-type lectin structure at the extracellular C-terminus which recognizes the ligand. LOX-1 activation by oxidized LDL causes endothelial changes such as decreased nitric oxide release and an increased expression of adhesion molecules. LOX-1 also binds activated platelets and apoptotic cells. The expression of LOX-1 is induced by proatherogenic conditions such as hyperlipidemia, hypertension and diabetes and as such appears to contribute to the pathogenesis of vascular disorders, particularly atherosclerosis. It can be cleaved by an unknown protease at the extracellular juxtamembrane region to release the soluble form (aa58-273) of LOX-1, recognized by DS-MB-03380

Purification: Purified

Immunogène: Recombinant soluble LOX-1 expressed in E.coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA, Western Blotting

Restrictions: For Research Use only

Stockage

Concentration: IgG concentration 1.0 mg/ml

Buffer: Phosphate buffered saline pH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C

Détails sur OLR1

Antigène: OLR1 (Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1))

Autre désignation: LOX-1 (OLR1 Produits)

Synonymes: anticorps OLR1, anticorps LOX1, anticorps Olr1, anticorps CLEC8A, anticorps LOXIN, anticorps SCARE1, anticorps SLOX1, anticorps LOX-1, anticorps SR-EI, anticorps Scare1, anticorps Oldlr1, anticorps Oldr1, anticorps PLOX-1, anticorps oxidized low density lipoprotein receptor 1, anticorps oxidized low density lipoprotein (lectin-like) receptor 1, anticorps OLR1, anticorps Olr1