IL-1 beta anticorps
Aperçu rapide pour IL-1 beta anticorps (ABIN641016)
Antigène
Voir toutes IL-1 beta (IL1B) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- Rabbit Anti-Chicken IL-1 beta
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Specificité
- This product recognizes chicken Interleukin 1 beta (chIL-1beta), which shares homology with mammalian IL-1beta. IL-1 is a major regulator in both innate and adaptive immune responses, plays an important role in the regulation of acute inflammation and has also been implicated in many other processes, including both fever and fibrinogen induction. The previous names by which IL-1 has been known includes lymphocyte activating factor, endogenous pyrogen, catabolin, hemopoietin-1, melanoma growth inhibition factor, and osteoclast activating factor, reflecting its widespread cell expression. Studies using chicken models have indicated physiological similarities between chIL-1beta and mammalian IL-1beta in relation to its neural distribution and several factors have been shown to induce chIL-1beta secretion, including protein kinase C (PKC), Calmodulin-dependent protein kinase, lipopolysaccharide, phorbol esters, calcium and silica. It neutralizes chicken IL-1 beta (1-2).
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Attributs du produit
- Cytokines/Chemokines/Growth Factors/Receptors
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Immunogène
- Antisera to chicken Interleukin 1 Beta were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography on protein G
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Isotype
- IgG
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Indications d'application
- ELISA, Functional Assays, Western Blotting
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Restrictions
- For Research Use only
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Concentration
- IgG concentration 0.5 mg/ml
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Buffer
- Phosphate buffered saline
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Agent conservateur
- Azide free
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Stock
- -20 °C
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Stockage commentaire
- -20°C
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- IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
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Autre désignation
- Interleukin-1 beta (IL-1b)
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Pathways
- Signalisation NF-kappaB, Interferon-gamma Pathway, Signalisation TLR, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome
Antigène
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